Name;GHRP-2
synonyms;D-ALA-BETA-(2-NAPHTHYL)-D-ALA-TRP-D-PHE-LYS AMIDE
D-ALA-D-2-NAL-ALA-TRP-D-PHE-LYS-NH2
D-ALA-D-NAL(2)-ALA-TRP-D-PHE-LYS-NH2 ACETATE SALT
(DES-ALA3,D-ALA1,D-2-NAL2)-GHRP-6
(DES-ALA3)-GHRP-2
(DES-ALA3)-GROWTH HORMONE-RELEASING PEPTIDE-2
(DES-ALA3)-KP-102
(DES-ALA3)-PRALMORELIN
(DES-ALA8,D-ALA6,D-2-NAL7,D-PHE10)-ALPHA-MSH (6-11) AMIDE
GHRP-2
GHRP-2 ACETATE
GROWTH HORMONE RELEASING PROTEIN-2
H-D-ALA-D-2-NAL-ALA-TRP-D-PHE-LYS-NH2
H-D-ALA-D-2-NAL-TRP-D-PHE-LYS-NH2
H-D-ALA-D-ALA(2-NAPHTHYL)-TRP-D-PHE-LYS-NH2
PRALMORELIN
(D-ALA1,D-2-NAL2)-GHRP-6 TRIFLUOROACETATE SALT
D-ala-B-(2-naphthyl)-D-ala-trp-D-phe-*lys amide
-2
d-ala-β-(2-naphthyl)-d-ala-trp-d-phe-lys amide
CAS;158861-67-7
EINECS(EC#);206-616-8
Molecular Formula;C45H55N9O6
MDL Number;MFCD05663458
Molecular Weight;817.97
Melting point ;149 - 151°C
Boiling point ;1265.3±65.0 °C(Predicted)
density ;1.270±0.06 g/cm3(Predicted)
storage temp. −20°C
solubility ;DMSO (Slightly, Sonicated), Water (Slightly)
form ;lyophilized powder
pka;13.40±0.46(Predicted)
color ;white to beige
Growth hormone releasing peptide 2;
GHRP-2 stands for growth hormone releasing peptide 2 (a type of growth hormone secretin). As the name suggests, the drug stimulates the release of growth hormone. GHRP-2 can be used as a treatment for GH deficiency in the pharmaceutical market. GHRP-2 is an effective stimulant for growth hormone release. Although it only increases the body's own ability to synthesize this hormone, given the right dose, it can also promote the production of very high levels of growth hormone compared to exogenous human growth hormone administration. And compared to growth hormone, it is more cost-effective. GHRP-2 is most commonly used in the bodybuilding world for fat loss and muscle gain as well as anti-aging purposes. The drug belongs to the growth hormone-releasing peptide (GHRP) class. These compounds may mimic the effects of Ghrelin, an endogenous gastrointestinal peptide hormone, to some extent. On an empty stomach (when not eating), the stomach secretes the hormone Ghrelin, which stimulates receptors in a variety of tissues, including the hypothalamus, pituitary gland and other parts of the brain, the sympathetic nervous system, the stomach, heart, pancreas, liver and intestines, and even fat tissue. Ghrelin is commonly found in the digestion and absorption of food, body composition and the regulation of glucose metabolism. In addition, relevant studies have shown that it can greatly stimulate appetite, affect taste, regulate sleep quality, stimulate gastrointestinal motility, emptying, promote lean body mass retention, improve cardiac output, reduce inflammation, insulin sensitivity. Ghrelin is an agonist for the growth hormone secretin receptor Ia (GHSRIa). Studies have shown that it can increase acute growth hormone release in the anterior pituitary gland and pulse growth hormone secretion 24 hours a day. This, in turn, may also support increased IGF-1 (insulin-like growth factor) production. Several other hormones secreted or connected by the pituitary gland, including ACTH (adrenocorticotropic hormone), cortisol, and prolactin, can also be stimulated in the presence of elevated levels of auxin releasing peptides. On the other hand, the hormone Ghrelin also helps to lower insulin production and suppress LH (luteinizing hormone) levels. Ghrelin, as a drug, may also have spillover effects in other areas of the body. This is the case with many GHRP analogues, but their effects are usually more targeted. GHRP-2 has a moderate tendency to increase levels of ACTH, cortisol, and prolactin. These are considered spillover effects to other systems. But it still seems to show some targeting: stimulating the release of growth hormone is estimated to be 200%-300% more effective than its predecessor, GHRP-6. At the same time, appetite-stimulating properties were significantly reduced. However, most users reported an increase in appetite after using GHRP-2. But the effect is not very strong and lasts a short time. In contrast, GHRP-2 is also thought to have no effect on wound healing. This may be related to a lower degree of spillover effect on cortisol.
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