CAS No.75696-02-5
Name: Cinolazepam
SynonymsOX-373;Gerodorm;Cinolazepam;2,3-Dihydro-7-chloro-5-(2-fluorophenyl)-2-oxo-1H-1,4-benzodiazepine-1-propanenitrile;1H-1,4-Benzodiazepine-1-propanenitrile, 7-chloro-5-(2-fluorophenyl)-2,3-dihydro-3-hydroxy-2-oxo-;3-[9-chloro-6-(2-fluorophenyl)-4-hydroxy-3-oxo-2,5-diazabicyclo[5.4.0] undeca-5,8,10,12-tetraen-2-yl]propanenitrile
CBNumber:CB91178291
Molecular Formula:C18H13ClFN3O2
Molecular Weight:357.771
MDL Number:MFCD00868001
Melting point；190-193°
Boiling point；643.5±55.0 °C(Predicted)
Density；1.39±0.1 g/cm3(Predicted)
form；A neat solid
pka；11.53±0.40(Predicted)
Description；
Cinolazepam is a benzodiazepine hypnotic introduced first in Austria for the treatment of sleep disturbance due to somatic or environmental factors. It has a half-life of 9 hr and effectively restores disturbed sleep to normal but does not significantly affect normal sleep patterns. This compound is well tolerated and has been reported to have no hang-over side effect after sleep.
Originator；Gerot (Austria)
Uses；
Cinolazepam is used as one of the substances for network-assisted prediction of potential drugs for addiction.
Definition；
ChEBI: A 1,4-benzodiazepinone compound having a 2-cyanoethyl substituent at the 1-position, a hydroxy substituent at the 3-position, a 2-fluorophenyl group at the 5-position and a chloro substituent at the 7-position, it has general properties similar to those of diazepam and has been used for the short-term management of sleep disorders.
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